Kuzhithurai Railway Station (also spelt Kulithurai Railway Station) is served by the Southern Railways. It is on the Thiruvananthapuram-Kanyakumari rail route. Bangalore Express, Kanyakumari Express, Thiruvananthapuram Central-Nagercoil Passenger, Madurai Passenger, Chennai-Egmore-Guruvayur Express, Cape Mumbai Express and Anantapuri Express pass through this station. The main city close to station is Nagercoil. The nearest airport is Trivandrum International Airport.