Uthirakosamangai and Erwadi are pilgrim centers close to Sayalkudi. Chitrangudi Bird Sanctuary, Gulf of Mannar Marine Biosphere Reserve, Adi Jagannatha Temple at Tirupullani and Kothandaramaswamy Temple at Dhanushkodi are among the prime spots that can be visited while in Sayalkudi.

Madurai Airport is 81 km north and Tuticorin Airport is 69 km south. Nearest railheads are Paramakkudi Railway Station and Ramanathapuram Railway Station. By road, Sayalkudi can be accessed from Aruppukkottai, Paramakudi, Kamudi, Kadaladi, Vilathikulam and Ramanathapuram.